Recent reviews have outlined numerous epidemiological investigations finding an association between increased PCa risk and gut and urinary microbiota [77, 78] and microbiota‐induced genetic toxins causing transmembrane serine protease 2—erythroblastosis virus E26 related gene fusions, which is known to be an early genetic event in PCa oncogenesis [78]. The gene discussed is TMPRSS2; the disease is posterior cortical atrophy.