GPX4 and colorectal carcinoma: SLC25A10 functions as an essential mtGSH transporter located within the mitochondrial inner membrane.45 Given our previous finding that INHBA positively regulates SLC25A10, we hypothesized that INHBA might inhibit mitochondrial ferroptosis in CRC cells by upregulating SLC25A10 to activate the mtGSH/GPX4 axis.