For instance, SLC1A4, a serine transporter implicated in spastic tetraplegia and microcephaly (OMIM# 616657), was significantly enriched in the Development group and dropped by 70% in adulthood (Fig. 3D, Table 1, Dunn’s multiple comparison test P value (Dunn’s P value) = 0.042). Here, SLC1A4 is linked to microcephaly.