In essence, ferroptosis is an iron‐dependent, non‐apoptotic cell death process that comprises many unique features, including abnormal metabolism and subsequent accumulation of iron, intracellular accumulation of iron‐induced ROS, enhanced lipid metabolism and peroxidation, and impairment of the system Xc−‐GSH‐GPX4 axis, etc. Studies have shown that corosolic acid inhibits EMT in lung cancer cells by promoting YAP‐mediated ferroptosis, and eriocitrin inhibits EMT in lung adenocarcinoma cells via triggering ferroptosis [32]. This evidence concerns the gene GPX4 and lung cancer.