To understand the molecular mechanism of IGSF10's tumour‐promoting effect on LUAD, we analysed the differential gene expression between high and low expression samples of IGSF10 in the TCGA‐LUAD database using DESeq2, and we identified 955 significantly upregulated genes and 561 significantly downregulated genes (Figure 5A). The gene discussed is IGSF10; the disease is neoplasm.