Previously established cutpoints classified AD status ("AD+," "AD-," or "Intermediate").<h4>Results</h4>Plasma p-tau<sub>217</sub>/Aβ<sub>42</sub> had the strongest association with known AD-related factors-MCI, ADD, future progression to MCI/ADD, age, and APOE ε4-compared to p-tau<sub>217</sub> and Aβ<sub>42</sub>/Aβ<sub>40</sub>. Here, MAPT is linked to Alzheimer disease.