In addition, Lyz can protect intestinal epithelium against bacterial infection(58) and enhance intestinal functions and gut microflora of piglets.(59) In swine feed, it can be supplemented as the alternative to growth-promoting subtherapeutic antibiotic.(60) Villin is the marker of absorptive cells,(61) its expression can assess recovery of the intestinal absorptive surface area.(62) In this study, we found that organic iron improved and maintained jejunal epithelial barrier and absorption function, as evidenced by increased mRNA expressions of Lyz, Villin, claudin-1, and ZO-1 in the jejunum. The gene discussed is CLDN1; the disease is bacterial infectious disease.