IRF8 and breast cancer: Additionally novel genes like IRF8, known for its role in hematopoietic lineage differentiation, Stat1, known for its role in innate and adaptive immunity, Znf384, which promotes EMT in breast cancer cells and is linked to Zeb1 (102), and the Krueppel-like factor Klf11, known for its role in extracellular matrix regulation by repression of Collagen 1a2 (103) and involvement in glucose metabolism (104) were highlighted.