MXI1 and neoplasm: The top list also included two cMyc regulating genes: Mxi1, a Max-binding tumor supressor that antagonizes cMyc among other things (93, 94) and Ztbt17 (aka Miz-1) which we have previously shown to regulate the neural crest stem cell pool via binding to c-Myc via a non-canonical pathway (95, 96).