CCR4 and cytomegalovirus infection: This is supported both by our previous observation that disruption of the CCR4-NOT complex leads to longer poly(A) tails on human mRNAs and hinders HCMV infection (25) and the separate demonstration using ribosome profiling of superior translational efficiency of HCMV mRNAs over host mRNAs (58) with a mechanism of selectivity that was hitherto unexplained.