In inflammatory injury, plant extract Maslinic acid promotes ALKBH5 recruitment of TXNIP mRNA in high glucose-induced HUVECs, enhances its m6A demethylation, reduces TXNIP mRNA stability and expression, inhibits reactive oxygen species (ROS) and pro-inflammatory factors such as TNF-α, IL-6, IL-1β, and alleviates endothelial inflammation and injury [160]. This evidence concerns the gene TXNIP and inflammatory response.