Anti-IgLON5 disease not only has antibodies against the IgLON5 protein but also shows a deposition of hyperphosphorylated tau in the tegmentum of the brainstem and hypothalamus, leading to progressive neurodegeneration similar to other tauopathies such as PSP [2]. This evidence concerns the gene IGLON5 and supranuclear palsy, progressive, 1.