NOS3 and endothelial dysfunction: Li et al. showed that in a human coronary endothelial cell (HCAEC) injury model, miR‐138 upregulation suppressed the PI3K/AKT/eNOS pathway, reduced proinflammatory cytokines (TNF‐α, IL‐6, and IL‐8), and attenuated endothelial dysfunction [32].