PRDX4 and Familial prostate cancer: Specifically, compared with normal prostate tissue, PRDX3 showed the most significant positive expression in PCa tissue(P<0.0001) (Figure 4C); In addition, there is also a significant difference in the positive expression of PRDX2 and PRDX4 in PCa tissues(P<0.001) (Figure 4B, D); PRDX1 followed closely behind once again(P<0.01) (Figure 4A); Finally, the positive expression of PRDX5 and PRDX6 was least significant in prostate cancer tissues(P<0.05) (Figures 4E, F).