Gene Set Enrichment Analysis (GSEA) showed that samples with high TICRR expression were significantly enriched in pathways linked to tumor malignancy, including epithelial-mesenchymal transition (EMT) (Figure 3C), E2F target genes (Figure 3D), G2M checkpoint (Figure 3E), mitotic spindle (Figure 3F), hypoxia (Figure 3G), PI3K-AKT-mTOR signaling (Figure 3H), and mTORC1 signaling (Figure 3I). The gene discussed is AKT1; the disease is neoplasm.