In contrast, HLA-A*02:01 was associated with reduced EBV activity and is protective against MS68 and EBV+ Hodgkin lymphoma.69 HLA molecules shape antigen-presentation preferences and thymic TCR repertoire formation.70 In addition, components of the antigen-processing pathway, including ERAP2, emerged as important regulators of EBV control. This evidence concerns the gene HLA-A and Hodgkins lymphoma.