HLA-C and type 1 diabetes mellitus: We also investigated the contribution of high-risk Human Leukocyte Antigens (HLA) type 1 diabetes variants in the major histocompatibility complex (MHC) within those diagnosed <2 years, 2–7 years, 7–13 years and >13 years to determine the role of these variants which play a key role in autoimmunity.