CP and cardiovascular disorder: Mutations in CP are associated with angiogenesis [68], CDH13 mutations are associated with atherosclerosis [69, 70] and cardiovascular disease [71], COL6A3 mutations are associated with ischemic stroke [72], myocardial infarction and hypertension [45], and descending and ascending aortic diameter [73], ELOVL6 mutations are associated with monocyte and platelet count [74], platelet count during second trimester, delivery, and postpartum [75] and thrombocytopenia [76], and NR3CD has been associated with hypertension [77].