GLP1R and Sepsis: Renal vascular conductance increased during sepsis (0.64 ± 0.59 ml/min/mmHg in GLP-1 group vs. 1.2 ± 0.17 ml/min/mmHg in vehicle group) during the intervention period, this remained relatively stable in both groups mean change 0.16 vs. 0.27 difference (95% CI) = − 0.1 (− 0.57–0.35) P = 0.61.