ALDH3A2 and gastric cancer: Subsequent correlation analyses revealed that ALDH3A2 expression was positively correlated with M1 markers and negatively correlated with M2 markers (Fig. 8B, C), which led us to further hypothesize that ALDH3A2-induced ferroptosis may modulate the tumor microenvironment by promoting TAMs polarization through the release of ferroptosis-associated molecule factors, thereby partially contributing to suppression of GC progression.