GPX4 and neoplasm: qPCR and immunoblotting analyses of tumor tissues isolated from implanted mice revealed that ALDH3A2 overexpression markedly increased the mRNA and protein levels of ALDH3A2 while significantly reducing the mRNA levels of SLC47A1, LONP1, and HSP60 (Fig. 10F) as well as the protein levels of SLC47A1, LONP1, HSP60, and GPX4 (Fig. 10G).