CD8A and rheumatoid arthritis: In CD8+ naïve/central‐memory T cells (Figure 2B), the pattern reversed: higher GSDMA expression was associated with lower risk of rheumatoid arthritis (OR = 0.88, 95% CI 0.80–0.96) and UC (OR = 0.52, 95% CI 0.40–0.68), and other traits were not significant; the pooled estimate in this lineage trended protective but was not significant (pooled OR = 0.90, 95% CI 0.77–1.05; I2 = 70%).