CD8A and neoplasm: 2022; Elewaut et al. 2024). Numerical continuation and bifurcation analysis revealed critical codimension-two organizing centers (Bogdanov–Takens and Bautin points) delineating transitions between tumor clearance, stable coexistence, and escape regimes. These findings extend the biological insights of Elewaut et al., who demonstrated that inflammatory monocytes acquire tumor-derived MHCI–peptide complexes and are essential for intratumoral restimulation of primed CD8+ T cells (Magen et al. 2023; Espinosa-Carrasco et al. 2024; Kruse et al. 2023; Elewaut et al. 2024).