The studies conducted to date include research by Yoshino et al. [14], who demonstrated that Polymyxin B considerably enhanced the generation of IgA in the mucosal secretions of vaccinated mice, demonstrating the mucosal adjuvanticity of Polymyxin B for influenza HA and SARS-CoV-2 S proteins in comparison to the antigen only. This evidence concerns the gene CD79A and influenza.