Obesity induces macrophage infiltration into adipose tissue and dysregulated adipokine secretion, leading to persistent elevation of inflammatory cytokines such as interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), and C-X-C motif chemokine ligand 10 (CXCL10) [2]. The gene discussed is IL6; the disease is Obesity.