Common MSAs include anti-Mi-2, anti-TIF1-γ, anti-NXP2, anti-SAE, and anti-MDA5, each linked to distinct risks (e.g., malignancy with TIF1-γ/NXP2; RP-ILD with MDA5) [9,15,16,17]. This evidence concerns the gene TRIM33 and interstitial lung disease.