In our study, a positive correlation of methylation and expression in the promoter region, and a negative correlation of the gene body for LPP, is associated with an increase in the expression of intragenic region as suggested by miR-28-5p level in tumor tissues, and to a lower extent in LPP expression in LUAD and LUSC (Figure 2A–D). The gene discussed is LPP; the disease is neoplasm.