Another study conducted by Nunez Lopez et al. [51] studied circulating extracellular vesicles from human serum samples and identified several phosphorylated kinases that are upregulated in the development and progression of T2D, including AKT1, GSK3B, LYN, MAP2K2, MYLK and PRKCD. The gene discussed is LYN; the disease is type 2 diabetes mellitus.