Despite the previously cited study [10] which indicated a negative, but not statistically significant, correlation between serum calprotectin and adiponectin (R= −0.27; p = 0.252), there are no detailed studies on the relationship between serum calprotectin and adiponectin in the context of obesity or metabolic syndrome. The gene discussed is ADIPOQ; the disease is obesity due to melanocortin 4 receptor deficiency.