CRP and Insulin resistance: In univariable regression analysis, higher levels of calprotectin were positively associated with the occurrence of cardiometabolic risk factors: overweight and abdominal obesity, CRP concentration ≥ 1 mg/L (indicating low-grade inflammation), increased HOMA-IR (related to insulin resistance), higher values of HbA1c (>32 mmol/mol; >median), decreased HDL-C and hypertriglyceridemia (≥1.69 mmol/L; ≥150 mg/dL).