There is existing literature indicating how human mastocytosis shows similarities with canine MCT, such as activating KIT mutations; this would suggest canines as a good translational animal model for humans [11], strengthening the concept that a multidisciplinary approach based on the emerging “One Health, One Medicine” paradigm could accelerate the development of novel therapies while enhancing our comparative understanding of cancer biology [12]. Here, KIT is linked to mastocytosis.