TP53 and myelodysplastic syndrome: The frequency of chromosome 5 abnormalities (del(5q)/monosomy 5) was markedly higher in TP53-mutant MDS (81.4 in multi-hit and 66.7% in mono-hit) than in TP53-WT tumors (4.3% in TP53-WT); the same applied to CK (88.6% vs. 11.5%) [84].