Other important limitations of the present study, in addition to the cross-sectional design, the use of urinary rather than serum albumin, the lack of information regarding the interval between functional and biochemical assessments, and the apparently healthy condition of the participants, concern the adaptations of the methods used to assess malnutrition and frailty, as well as the insufficient data available to evaluate the presence of sarcopenia according to the EWGSOP criteria, which has long been recognized as a consequence of malnutrition. The gene discussed is ALB; the disease is nutritional deficiency disease.