Adipokines, such as leptin and adiponectin, chemokines, such as CCL7, and metabolites, such as glucose and FFAs, were the targets selected to be quantified as they are key players in prostate tumorigenesis and are differentially secreted by adipocytes in obesity [6,36,37,38,39,40,41,42,43]. This evidence concerns the gene LEP and obesity due to melanocortin 4 receptor deficiency.