The most common genetic cause of ALS/FTD is a GGGGCC (G4C2) hexanucleotide repeat expansion in the intron 1 of chromosome 9 open reading frame 72 (C9orf72), observed in approximately 40% of familial and 12% of sporadic cases [6,7]. This evidence concerns the gene C9orf72 and amyotrophic lateral sclerosis.