In HCC, MTA expression is associated with matrix metalloproteinase (MMP) and interleukin-8 (IL-8) transcription in HCC cells in vitro, accompanied by enhanced proliferation and activation of the transcription factor nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) [56]. Here, CXCL8 is linked to hepatocellular carcinoma.