As a signaling receptor for the proinflammatory cytokine macrophage migration inhibitory factor (MIF), CD74 triggers intracellular signaling pathways involved in immune responses, inflammation, neuroinflammation, atherosclerosis, cell migration, and wound healing [4,16,17,18], as well as tissue repair in various parts of the body [19,20]; it is also involved in skin-aging mechanisms [21]. This evidence concerns the gene MIF and atherosclerosis.