In contrast, in the cancer cell lines (Saos-2, 5637, DLD-1, and HLF), not only E2WT-ARF (−13) but also ERE73 (1 + 2)-ARF (−13) and ERE73 (3 + 4)-ARF (−13) were repressed by PSM.7-LP (Figure 2E). The gene discussed is CDKN2A; the disease is cancer.