Outside the Latin American region, the adult FA prevalence rate estimated in the present study is lower than the rates reported in North Americans (10.8%) [11], similar to Canadians (5.7%), and falls within the upper end of the prevalence range for probable IgE-mediated FA (0.3% to 5.6%) reported in the EuroPrevall study [10]. The gene discussed is IGHE; the disease is Friedreich ataxia.