Furthermore, to determine which variables were associated with IT need.<h4>Design/methods</h4>Retrospective analysis in a single centre cohort including 1,782 women screened at median 12 (11-14) weeks of pregnancy for thyroid disorders (TSH, free T4 (FT4), and TPOAb) and for GDM with an oral glucose tolerance test at 24-28 weeks. The gene discussed is CD4; the disease is thyroid gland disorder.