SLC5A2 and diabetes mellitus: Regarding SGLT2 inhibitors (SGLT2is), Silverii et al. [21] found no significant association with FG in a meta-analysis of randomized controlled trials (odds ratio [OR] 0.41, 95% confidence interval [CI] 0.09–1.82), while Azmi et al. [15] reported rare but severe cases in patients with diabetes using SGLT2is, warranting clinical caution.