CD58 and neoplasm: Univariate and multivariate Cox proportional hazards regression analyses identified high CD58 expression (hazard ratio [HR] = 1.895, 95% confidence interval [CI]: 1.745–2.057, p < 0.001) and advanced tumor stage (HR = 1.326, 95% CI: 1.187–1.482, p < 0.001) as independent prognostic risk factors (Figures 4A, B).