The incidence of positive urinary occult blood and hemorrhagic cystitis in TA-TMA and grade III-IV aGVHD groups were higher than those in aGVHD I-II group, and the levels of platelet and serum ALB in TA-TMA and grade III-IV aGVHD groups were lower than those in grade I-II aGVHD group. This evidence concerns the gene ALB and hemorrhagic cystitis.