Anti-MDA5+ dermatomyositis (anti-MDA5+ DM), a distinct subtype of DM, is characterized by serum reactivity against the autoantigen MDA5 and unique cutaneous manifestations such as Gottron’s papules and heliotrope rash, often with absent or atypical myositis symptoms (1, 7, 8). The gene discussed is IFIH1; the disease is myositis disease.