YAP1 and neoplasm: In a separate mechanism, lncBRM recruits the brahma-related gene (BRM) to the switch/sucrose non-fermentable (SWI/SNF) chromatin remodeling complex, activating YAP1 signaling to maintain Liver-CSC stemness and tumor-initiating capacity (435), while lncRNA MALAT1 enhances Liver-CSC properties by sponging miR-375, which derepresses YAP1 expression (436).