Enrichment of the 33 PI3K/AKT/mTOR-related DEGs was primarily observed in KEGG pathways such as PI3K/AKT (hsa04151), MAPK (hsa04010), JAK–STAT (hsa04630), autophagy-animal (hsa04140), apoptosis (hsa04210), insulin signaling (hsa04910), prostate cancer (hsa05215), and choline metabolism in cancer (hsa05231). This evidence concerns the gene AKT1 and Familial prostate cancer.