CDKN2A and glioblastoma: 40 Changes in CDKN2A expression may thus be therapeutically relevant and a prognostic marker in patients with glioblastomas. 40 Here, we assessed CDKN2A/B chromosomal loss using the CNV profiles that are generated by applying the Infinium Methylation EPIC Bead Chip array. 34 We found that loss of CDKN2A/B is found in RTK II glioblastomas (Figure 2C).