BIRC3 and liver cancer: However, the levels of XIAP, cIAP-1 and cIAP-2, remained unchanged in the SFN-treated cervical carcinoma cells, as SFN substantially inhibited the levels of cIAP-1 expression in liver cancer cells without affecting the XIAP and cIAP-2 expression 36, although SFN efficiently triggered apoptosis in both malignant cell lines.