Diels [Apiaceae; A. sinensis radix] modulates inflammatory and autophagic pathways, inhibits NLRP3 inflammasome activation, and prevents microglial pyroptosis, offering neuroprotection in ischemic stroke (Hu et al., 2020; Luo et al., 2021; Wang et al., 2022). The gene discussed is NLRP3; the disease is ischemic stroke.