To further investigate the effects of UFH on coagulation and inflammatory responses during sepsis, the mRNA expression levels of TF, Fib, IL-1α and HPA were quantified in lung tissues (Supplementary Figures S5A–5C, 5E), while a decreased expression level of syndecan-1 (Supplementary Figures S5D). The gene discussed is IL1A; the disease is Sepsis.