Several studies indicated that the APOE ε4 allele can predict dementia risk after falls.[7,49,60] Another study examined the risk of falls influenced by the APOE ε4 allele in 810 carriers of the allele.[61] Previous research indicated that high genetic risk is associated with smaller hippocampal volume and white matter lesions or hyperintensities,[62, 63, 64] which may contribute to increased dementia risk. This evidence concerns the gene APOE and dementia.