Significant intergroup differences were observed in diabetes duration, biliary obstruction, fasting glucose, total bilirubin, direct bilirubin, bile acid, albumin, triglyceride, and CEA (p < 0.05), while no significant differences were found in age, sex, BMI, cholesterol, hypertension, smoking, or CA19-9 (Supplementary Table 2). The gene discussed is ALB; the disease is hypertensive disorder.