Interestingly the authors also found that the IRF5/IKKb PBAE complexes increased T cell infiltration 10.6-fold for CD8+ and 3.5-fold for CD4+ T cells which likely contributed to some of the anti-tumour potency seen, which was further confirmed through CD8+ T cell suppression with a monoclonal antibody. Here, IKBKB is linked to neoplasm.