The reversal of NCOA4, autophagy‐related proteins, and mitochondrial morphology after the incorporation of 3‐MA also initially demonstrated that DAU could exert its inhibitory effect on BLCA cells through ferritinophagy, illustrating that focusing on ferritinophagy may be an efficient strategy to enhance ferroptosis impaction, especially in tumors such as BLCA, which are ineffective against conventional treatment. The gene discussed is NCOA4; the disease is bladder transitional cell carcinoma.